Introduction: In this enlightening episode of the podcast, host Latt Mansor engages in a captivating conversation with Dr. Anthony Gustin, delving into the complex world of seed oils, the challenges posed by our current food system, and the transformative potential of the ketogenic diet.

The Artificial Environment and Genetic Mismatch: Dr. Gustin starts by framing the discussion around the idea that humans find themselves in an artificial environment, one that differs significantly from the genetic blueprint we are designed for. He emphasizes the importance of moving forward rather than attempting to recreate ancestral living. It's about finding solutions that align with our genes and mimic the environment that best suits our genetic makeup.

The Missing Investigation: Dr. Gustin raises an intriguing point, likening the situation to observing a sick squirrel. If we witnessed a squirrel coughing, limping, and growing to an abnormal size, we would instinctively investigate the cause of the problem. However, he points out that we have lost this inquisitive approach when it comes to our own health. It is crucial to identify the factors that take us off track and understand the interventions needed to restore our natural balance.

Seed Oils: The Primary Culprit? When asked about the biggest factors derailing our metabolic health, Dr. Gustin expresses his belief that seed oils, upon examining the available data, stand out as the top contributor to metabolic dysfunction. These oils, particularly those rich in linoleic acid, seem to inflict substantial damage on our bodies. Furthermore, the combination of seed oils and high-carbohydrate diets, prevalent in processed foods, poses the most significant risk to our health.

Rethinking Carbohydrates: Dr. Gustin challenges the notion that all carbohydrates are inherently harmful. Drawing attention to Asian cultures like Japan, where diets traditionally revolve around rice consumption, he highlights that carbohydrates alone may not be the primary issue. However, he emphasizes that when combined with seed oils, the negative impact intensifies. The rising incidence of diabetes in Japan parallels the increase in seed oil consumption, presenting a compelling correlation.

A Smoking Gun: Throughout the discussion, Dr. Gustin presents a compelling case, supported by ancestral philosophy, epidemiology, clinical trials, and mechanistic research. The evidence appears to point directly at seed oils as a significant contributor to metabolic dysfunction. By unraveling this smoking gun, we gain insights into how we can restore metabolic pathways and potentially improve our health outcomes.

Conclusion: In this thought-provoking episode, Latt Mansor and Dr. Anthony Gustin shed light on the role of seed oils, the flaws within our food system, and the potential benefits of adopting a ketogenic diet. By understanding the impact of seed oils and their combination with carbohydrates, listeners are empowered to make informed decisions about their health, paving the way for a more optimized and balanced lifestyle.

In this episode, you'll discover:

  • Genetic Mismatch: Humans live in an artificial environment that differs from our genetic blueprint. It's important to find solutions that align with our genes.
  • Seed Oils: Dr. Gustin believes seed oils, especially those high in linoleic acid, are the primary culprit behind metabolic dysfunction.
  • Seed Oils + Carbohydrates: The negative impact intensifies when seed oils are combined with high-carbohydrate diets. This combination poses significant risks to our health.

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Dr. Latt Mansor:

Do you think that sea oil is one of the main culprit that is causing this metabolic health dysfunction and what are they?

Anthony Gustin:

The framework in which I view it is that we are in an artificial environment and whenever you take an organism and put it into a different environment than it, than is genetically meant to be.

Bad things are gonna happen. And I'm not a huge proponent, I don't think it's possible to go back. So I think a lot of people want me into like the ancestral paleo, paleo sort of like tr trad life kind of movement. And I don't think that's the case. I think we need to figure out solutions moving forward.

And sometimes that's mimicking the environment that best matches our jeans. And so you have, for example, if you look at a squirrel, then you saw a squirrel at the side. And it was coughing and it was three times the size and it was limping along; you would ask, what is going on with this animal? And you would be looking around about what was causing the problem.

And we are not doing that anymore. And I think what, what generally happens when people, they think this way of like, okay, I understand the concept of there's this environmental mismatch with genes, which leads to these issues. A lot of times, there is also a resultant. Dysfunction or disease that needs an artificial intervention.

And so, for example, if a train is running and tracks smoothly and it flies off the tracks, cause the tracks are bent, the bent tracks the artificial environment that led to a, a disease or, or dysfunction of the, the train off the tracks. If you fix the normal environment, which is necessary for the train to run again, it doesn't mean that the train's gonna run again.

You need an inter intervention of taking that train and putting it back on the tracks. But you also need a restoration of the natural, uh, ecosystem, which is the tracks. What we tend to do is mimic the natural environment, maybe eat some good foods, but don't look at the underlying issue of fixing, the intervention.

So like what are the biggest things? Is this kind of how I think about it that takes us off of tr off the tracks. And then what are the biggest things we need to do to then get back on track? And this is kind of like to go full circle around keto and metabolic dysfunction and carbohydrates, things like that.

I have now shifted my belief to, to thinking that the number one, I think this is a very multifactorial thing. We like, like I said, I had filled four pages into my notebook. Cause all the things that, that take us off a track and how our environment is screwed up. I think C oil is, are probably number one thing looking into the data.

That leads to metabolic dysfunction, the intervention coming back. I think keto is a tremendous tool to restoring that pathway, reducing carbohydrates. And then the narrative when I was going through is even the book that I wrote, keto answers around this was too much carbohydrates leads to metabolic dysfunction.

So decrease carbohydrates and you should decrease the metabolic dysfunction. And it's a very simplistic way to view it, I think. Yes, increase carbohydrates, especially increase. Ultra-processed carbohydrates lead to a lot of issues. We, uh, like you can't deny that, but I think increased seed oils, plants, citrated, fatty acid acids, linoleic acid specifically lead to even more damage.

And the worst thing is to eat both of these in combination, which is most of the processed food that we eat, packaged free, the wheat. So I think the sort of one two punch is the worst thing for sure. And then if you were then to extract them, It's then seed oils and then carbohydrates on the mo on their own.

I just, there's so many examples that I have of people eating a lot of carbohydrates, not having any metabolic dysfunction. Take Japanese culture, for example, the most Asian, Asian cultures. This was like a paradox. Th this was basically like the modern version of the French paradox where we said, oh, these French people have are eating butter.

Why aren't, why aren't they have heart disease? Well, it turns out the butter wasn't the problem. And the same thing with Asian cultures. Like, oh, all these Asian people are eating so much rice and things like that. Like why aren't they, why don't they have diabetes? Well, it turns out it wasn't the carbohydrates problem in the first place and that you start looking at, then the incidence of diabetes in J Japan is going through the roof.

And then you overlay that in the chart ofs, oil consumption. And when they started incorporating that, and it looks the same as smoking and lung cancer. And we go on and on and on about, you know, from all the way from ancestral philosophy to epidemiology, to clinical trials, mechanistic stuff, et cetera. It seems like quite a smoking gun to me.

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